Benzo-1,3-dioxole-5-acetic acid → HCID 178520187, compound

Participants

Reaction Steps

The title compound, white solid (113 mg, 92%), MS (ISP) m/z=493.3 [(M+H)+], mp 187° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 2-(benzo[d][1,3]dioxol-5-yl)-acetic acid.

Provenance & Evidence