(+-)-Tetrahydro-2-furoic acid → HCID 178523736, compound

Participants

Reaction Steps

The title compound, white solid (62 mg, 58%), MS (ISP) m/z=429.3 [(M+H)+], mp 145° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and (RS)-tetrahydro-furan-2-carboxylic acid.

Provenance & Evidence