2-Butynoic acid → HCID 178454565, compound

Participants

Reaction Steps

The title compound, white solid (80 mg, 81%), MS (ISP) m/z=397.3 [(M+H)+], mp 176° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and but-2-ynoic acid.

Provenance & Evidence