trans-3-pentenoic acid → HCID 178447395, compound

Participants

Reaction Steps

The title compound, white solid (92 mg, 89%), MS (ISP) m/z=413.4 [(M+H)+], mp 170° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and (E)-pent-3-enoic acid.

Provenance & Evidence