3-Methyl-2-butenoic acid → HCID 178447397, compound

Participants

Reaction Steps

The title compound, white solid (92 mg, 89%), MS (ISP) m/z=413.5 [(M+H)+], mp 183.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 3-methyl-but-2-enoic acid.

Provenance & Evidence