tert-Butylacetic acid → HCID 178445245, compound

Participants

Reaction Steps

The title compound, off-white solid (98 mg, 92%), MS (ISP) m/z=429.4 [(M+H)+], mp 193° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 3,3-dimethyl-butanoic acid.

Provenance & Evidence