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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260790Generated: November 1, 2026

Pivalic acid → HCID 178447396, compound

https://huagongshe.com/reaction/1260790

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPivalic acidHCID 6417—
ReactantHCID 178478590HCID 178478590—
ProductHCID 178447396HCID 178447396—

Reaction Steps

The title compound, white solid (78 mg, 75%), MS (ISP) m/z=415.5 [(M+H)+], mp 194.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 2,2-dimethyl-propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470828B2
Source datasetuspto-grants-2013_06
ORD IDord-ac817190091347449ae9e656f915f05a
Source noteuspto-grants-2013_06