Oxane-3-carboxylic acid → HCID 178523737, compound

Participants

Reaction Steps

The title compound, white solid (99 mg, 90%), MS (ISP) m/z=443.5 [(M+H)+], mp 203° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and (RS)-tetrahydro-pyran-3-carboxylic acid.

Provenance & Evidence