Methyl 3-oxetaneacetate → HCID 178520368, compound

Participants

Reaction Steps

The title compound, white solid (91 mg, 85%), MS (ISP) m/z=429.3 [(M+H)+], mp 175° C., was prepared in accordance with the general method of example 5 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and methyl 2-oxetan-3-yl-acetate.

Provenance & Evidence