(R)-3-hydroxypentanoic acid → HCID 178456104, compound

Participants

Reaction Steps

The title compound, white solid (56 mg, 52%), MS (ISP) m/z=431.5 [(M+H)+], mp 146° C., was prepared in accordance with the general method of example 5 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and (R)-3-hydroxy-pentanoic acid.

Provenance & Evidence