HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260848Generated: October 27, 2026
1-(Bromomethyl)-3-chlorobenzene → 1-(3-Chlorobenzyl)-2-imino-1,2-dihydropyridine-3-carboxamide hydrobromide
https://huagongshe.com/reaction/1260848
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-(Bromomethyl)-3-chlorobenzene | HCID 69838 | — |
| Reactant | 2-Aminopyridine-3-carboxamide | HCID 506623 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-(3-Chlorobenzyl)-2-imino-1,2-dihydropyridine-3-carboxamide hydrobromide | HCID 68661897 | 36% |
Reaction Steps
To a solution of 2-aminonicotinamide (0.1 g) in N,N-dimethylformamide (3 ml) was added 1-(bromomethyl)-3-chlorobenzene (0.3 g), and the mixture was stirred at 80° C. for 15 hr. The precipitated crystals were collected by filtration and washed with ethyl acetate to give the title compound (90 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08470859B2 |
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| Source dataset | uspto-grants-2013_06 |
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| ORD ID | ord-3f284f2d52a6409190995c17568b0513 |
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| Source note | uspto-grants-2013_06 |
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