1-(Bromomethyl)-3-chlorobenzene → HCID 68661597, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-amino-5-cyanonicotinamide (0.15 g) in N,N-dimethylformamide (3 ml) was added 3-chlorobenzylbromide (0.29 g), and the mixture was stirred at 100° C. for 8 hr. The reaction mixture was diluted with ethyl acetate. The precipitate was filtered and washed with ethyl acetate. The obtained precipitate was recrystallized from methanol-ethyl acetate to give the title compound (0.09 g).

Provenance & Evidence