HCID 21999886, compound → HCID 68662727, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-amino-5-chloronicotinamide (0.15 g) in N,N-dimethylformamide (3 ml) was added 2-(bromomethyl)-1-methoxy-4-(methylsulfonyl)benzene (0.29 g), and the mixture was stirred at 100° C. for 4 hr. The reaction mixture was diluted with ethyl acetate. The precipitate was collected by filtration and washed with ethyl acetate. The obtained precipitate was recrystallized from methanol-ethyl acetate to give the title compound (110 mg).

Provenance & Evidence