3-(Trifluoromethyl)benzylamine → HCID 68661977, compound

HRID 1260870Notes

Reaction equation

HRID 1260870 reaction equation
[C:1]([CH:3]([CH:7]1[C:11]([Cl:12])=[C:10](Cl)C(=O)O1)[C:4]([NH2:6])=[O:5])#[N:2].[F:15][C:16]([F:26])([F:25])[C:17]1[CH:18]=[C:19]([CH2:23][NH2:24])[CH:20]=[CH:21][CH:22]=1>>[ClH:12].[Cl:12][C:11]1[CH:7]=[C:3]([C:4]([NH2:6])=[O:5])[C:1](=[NH:2])[N:24]([CH2:23][C:19]2[CH:20]=[CH:21][CH:22]=[C:17]([C:16]([F:15])([F:25])[F:26])[CH:18]=2)[CH:10]=1

Participants

3

Reactant 2

HCID 759623-(Trifluoromethyl)benzylamineHCID 5417922-Cyano-2-(3,4-dichloro-5(2H)-oxo-2-furyl)acetamide

Product 1

HCID 68661977HCID 68661977, compound

Procedure

According to the method of Example 160, 2-cyano-2-(3,4-dichloro-5-oxo-2,5-dihydrofuran-2-yl)acetamide was reacted with 1-[3-(trifluoromethyl)phenyl]methanamine to give the title compound.

Sources & evidence

ORD record
ord-684aad11d81640c3904bffd203a4ba30
Source dataset
uspto-grants-2013_06
Patent number
US08470859B2

Reaction notes

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