2-Cyano-2-(3,4-dichloro-5(2H)-oxo-2-furyl)acetamide → HCID 68662312, compound

HRID 1260872Notes

Reaction equation

HRID 1260872 reaction equation
[C:1]([CH:3]([CH:7]1[C:11]([Cl:12])=[C:10](Cl)C(=O)O1)[C:4]([NH2:6])=[O:5])#[N:2].[F:15][C:16]1[CH:21]=[C:20]([F:22])[C:19]([F:23])=[CH:18][C:17]=1[CH2:24][NH2:25]>>[ClH:12].[Cl:12][C:11]1[CH:7]=[C:3]([C:4]([NH2:6])=[O:5])[C:1](=[NH:2])[N:25]([CH2:24][C:17]2[CH:18]=[C:19]([F:23])[C:20]([F:22])=[CH:21][C:16]=2[F:15])[CH:10]=1

Participants

3

Reactant 2

HCID 5417922-Cyano-2-(3,4-dichloro-5(2H)-oxo-2-furyl)acetamideHCID 27770442,4,5-Trifluorobenzylamine

Product 1

HCID 68662312HCID 68662312, compound

Procedure

According to the method of Example 160, 2-cyano-2-(3,4-dichloro-5-oxo-2,5-dihydrofuran-2-yl)acetamide was reacted with 1-(2,4,5-trifluorophenyl)methanamine to give the title compound.

Sources & evidence

ORD record
ord-a34dbc42e2b5461b9a45a2994188ddb7
Source dataset
uspto-grants-2013_06
Patent number
US08470859B2

Reaction notes

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