2-Cyano-2-(3,4-dichloro-5(2H)-oxo-2-furyl)acetamide → HCID 68662337, compound

HRID 1260877Notes

Reaction equation

HRID 1260877 reaction equation
[C:1]([CH:3]([CH:7]1[C:11]([Cl:12])=[C:10](Cl)C(=O)O1)[C:4]([NH2:6])=[O:5])#[N:2].[NH2:15][C@H:16]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:18][CH2:17]1>>[ClH:12].[Cl:12][C:11]1[CH:7]=[C:3]([C:4]([NH2:6])=[O:5])[C:1](=[NH:2])[N:15]([C@H:16]2[C:24]3[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=3)[CH2:18][CH2:17]2)[CH:10]=1

Participants

3

Reactant 2

HCID 5417922-Cyano-2-(3,4-dichloro-5(2H)-oxo-2-furyl)acetamideHCID 2733933(R)-(-)-1-Aminoindan

Product 1

HCID 68662337HCID 68662337, compound

Procedure

According to the method of Example 168, 2-cyano-2-(3,4-dichloro-5-oxo-2,5-dihydrofuran-2-yl)acetamide was reacted with (R)-(−)-aminoindane to give the title compound.

Sources & evidence

ORD record
ord-17e7467c46d34c77b4e0ae76582298cf
Source dataset
uspto-grants-2013_06
Patent number
US08470859B2

Reaction notes

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