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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 126091Generated: October 26, 2026

Dimethyl Sulfoxide → 2-Amino-N-(5-(4-chloro-phenoxy)-thiophen-2-ylmethyl)-nicotinamide

https://huagongshe.com/reaction/126091

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantWaterHCID 962—
ReactantAcetonitrileHCID 6342—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTriethylamineHCID 8471—
ReactantHexafluorophosphateHCID 9886—
Reactant2-Aminonicotinic acidHCID 72930—
ReactantBenzotriazol-1-yl-tris(dimethylamino)phosphaniumHCID 10938827—
ReactantHCID 23130383HCID 23130383—
Product2-Amino-N-(5-(4-chloro-phenoxy)-thiophen-2-ylmethyl)-nicotinamideHCID 23130691—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-94bc359ff26e49ea823057bd6548cc69
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)