Benzoyl chloride → HCID 68932060, compound

HRID 1260976Notes

Reaction equation

Cl.[Cl:2][C:3]1[CH:34]=[CH:33][C:6]([C:7]([N:9]([C@@H:11]2[CH2:16][CH2:15][N:14]([C:17]([CH:19]3[CH2:24][CH2:23][CH2:22][NH:21][CH2:20]3)=[O:18])[CH2:13][C@H:12]2[C:25]2[CH:30]=[CH:29][C:28]([Cl:31])=[C:27]([Cl:32])[CH:26]=2)[CH3:10])=[O:8])=[CH:5][CH:4]=1.[C:35](Cl)(=[O:42])[C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1>>[Cl:2][C:3]1[CH:4]=[CH:5][C:6]([C:7]([N:9]([C@@H:11]2[CH2:16][CH2:15][N:14]([C:17]([CH:19]3[CH2:24][CH2:23][CH2:22][N:21]([C:35]([C:36]4[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=4)=[O:42])[CH2:20]3)=[O:18])[CH2:13][C@H:12]2[C:25]2[CH:30]=[CH:29][C:28]([Cl:31])=[C:27]([Cl:32])[CH:26]=2)[CH3:10])=[O:8])=[CH:33][CH:34]=1

Participants

Reactant 2

HCID 7412Benzoyl chloride

HCID 68934091HCID 68934091, compound

Product 1

HCID 68932060HCID 68932060, compound

Procedure

Using the compound obtained in Example 542 and benzoyl chloride, and by the reaction and purification in the same manner as in Example 39, the title compound was obtained.

Workup

customby the reaction and purification in the same manner as in Example 39

Sources & evidence

ORD record: ord-0d704d85680243f7a00aa0968d0c8096
Source dataset: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08470816B2

Reaction notes

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