Benzoyl chloride → HCID 68932294, compound

HRID 1260977Notes

Reaction equation

Cl.[Cl:2][C:3]1[CH:34]=[CH:33][C:6]([C:7]([N:9]([C@@H:11]2[CH2:16][CH2:15][N:14]([C:17]([CH:19]3[CH2:24][CH2:23][CH2:22][CH2:21][NH:20]3)=[O:18])[CH2:13][C@H:12]2[C:25]2[CH:30]=[CH:29][C:28]([Cl:31])=[C:27]([Cl:32])[CH:26]=2)[CH3:10])=[O:8])=[CH:5][CH:4]=1.[C:35](Cl)(=[O:42])[C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1>>[Cl:2][C:3]1[CH:34]=[CH:33][C:6]([C:7]([N:9]([C@@H:11]2[CH2:16][CH2:15][N:14]([C:17]([CH:19]3[CH2:24][CH2:23][CH2:22][CH2:21][N:20]3[C:35]([C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)=[O:42])=[O:18])[CH2:13][C@H:12]2[C:25]2[CH:30]=[CH:29][C:28]([Cl:31])=[C:27]([Cl:32])[CH:26]=2)[CH3:10])=[O:8])=[CH:5][CH:4]=1

Participants

Reactant 2

HCID 7412Benzoyl chloride

HCID 68931068HCID 68931068, compound

Product 1

HCID 68932294HCID 68932294, compound

Procedure

Using the compound obtained in Example 545 and benzoyl chloride, and by the reaction and purification in the same manner as in Example 39, the title compound was obtained.

Workup

customby the reaction and purification in the same manner as in Example 39

Sources & evidence

ORD record: ord-c9a1a94cab694c1ab0bb131d06482a40
Source dataset: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08470816B2

Reaction notes

Loading…