Thionyl Chloride → HCID 58087452, compound

HRID 1261027Notes

Reaction equation

HRID 1261027 reaction equation
[CH2:1]([S:4]([NH:7][C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11](O)=[O:12])(=[O:6])=[O:5])[CH2:2][CH3:3].S(Cl)([Cl:19])=O>>[CH2:1]([S:4]([NH:7][C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11]([Cl:19])=[O:12])(=[O:6])=[O:5])[CH2:2][CH3:3]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 162282623-[(Propane-1-sulfonyl)amino]benzoic acid

Product 1

HCID 58087452HCID 58087452, compound

Procedure

A solution of 3-(propane-1-sulfonylamino)-benzoic acid (76, 1.20 g, 4.93 mmol) in thionyl chloride was heated to reflux for 3.0 hours. Evaporation of the solvent gave compound 77 as white solid that was used for the next step.

Workup

  1. temperatureto reflux for 3.0 hours
  2. customEvaporation of the solvent

Sources & evidence

ORD record
ord-acd0f00ba1ce45a1927d95672fbd4cef
Source dataset
uspto-grants-2013_06
Patent number
US08470818B2

Reaction notes

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