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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1261036Generated: November 2, 2026

5-isopropenyl-1H-pyrrolo[2,3-b]pyridine → 5-isopropyl-1H-pyrrolo[2,3-b]pyridine

https://huagongshe.com/reaction/1261036

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-isopropenyl-1H-pyrrolo[2,3-b]pyridineHCID 58086810—
CatalystPalladium hydroxideHCID 9942167—
SolventTetrahydrofuranHCID 8028—
Product5-isopropyl-1H-pyrrolo[2,3-b]pyridineHCID 59928720—

Reaction Steps

To 5-isopropenyl-1H-pyrrolo[2,3-b]pyridine (98, 0.080 g, 0.501 mmol) in tetrahydrofuran (5.0 mL) was added 20% palladium hydroxide on carbon (5.0 mg). The reaction was stirred under hydrogen at 40 psi for 30 minutes. The reaction mixture was filtered and concentrated to give the compound (99, 0.078 g, 96%). MS (ESI) [M+H+]+=161.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470818B2
Source datasetuspto-grants-2013_06
ORD IDord-2295e5b476104f3899e1ae8249de0118
Source noteuspto-grants-2013_06