HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1261166Generated: November 3, 2026
Aniline → N-phenyl-1H-pyrrolo(2,3-b)pyridin-3-amine
https://huagongshe.com/reaction/1261166
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | Sulfolane | HCID 31347 | — |
| Reactant | 3-Bromo-1H-pyrrolo[2,3-b]pyridine | HCID 5523659 | — |
| Product | N-phenyl-1H-pyrrolo(2,3-b)pyridin-3-amine | HCID 24180721 | — |
Reaction Steps
To 10 mg of 3-bromo-1H-pyrrolo[2,3-b]pyridine 582 was added 0.4 mL of sulfolane and aniline (2-3 equiv). The vial was sealed and heated at 180° C. for 10 minutes. After cooling, the desired compound was isolated by preparative HPLC/MS.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08470818B2 |
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| Source dataset | uspto-grants-2013_06 |
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| ORD ID | ord-3d8bc217ceba4bb2b14fa30dcd0f306a |
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| Source note | uspto-grants-2013_06 |
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