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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1261263Generated: November 1, 2026

7-Chlorothieno[3,2-b]pyridine → 7-(2-Fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine

https://huagongshe.com/reaction/1261263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Chlorothieno[3,2-b]pyridineHCID 11275251—
Reactant7-(2-fluoro-4-nitrophenoxy)-N,N-dimethylthieno[3,2-b]pyridine-2-carboxamideHCID 59424475—
Product7-(2-Fluoro-4-nitrophenoxy)thieno[3,2-b]pyridineHCID 5942468245%

Reaction Steps

Starting from the chloride 2 (scheme 1) and following the procedure described above for the synthesis of compound 6 (scheme 1, example 1), title compound 168 was obtained in 45% yield. LRMS (M+1) 290.3 (100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470850B2
Source datasetuspto-grants-2013_06
ORD IDord-cb07648ff5f94a9eac21125d8defa5f5
Source noteuspto-grants-2013_06