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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1261284Generated: November 2, 2026

4-(2-(4-(7-(4-Nitrophenoxy)thieno[3,2-b]pyridin-2-yl)phenoxy)ethyl)morpholine → 4-(2-(4-(2-Morpholinoethoxy)phenyl)thieno[3,2-b]pyridin-7-yloxy)benzenamine

https://huagongshe.com/reaction/1261284

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-(4-(7-(4-Nitrophenoxy)thieno[3,2-b]pyridin-2-yl)phenoxy)ethyl)morpholineHCID 59424464—
Reactant1-(4-(7-Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yloxy)-3-fluorophenyl)-3-(2-phenylacetyl)thioureaHCID 86604187—
Product4-(2-(4-(2-Morpholinoethoxy)phenyl)thieno[3,2-b]pyridin-7-yloxy)benzenamineHCID 5942441569%

Reaction Steps

Starting from the compound 201 and following the procedure described above for the compound 162 (scheme 31), title compound 202 was obtained in 69% yield. LRMS (M+1) 448.2 (100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470850B2
Source datasetuspto-grants-2013_06
ORD IDord-be98017537fc45d59e16fa48b9805d09
Source noteuspto-grants-2013_06