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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1261341Generated: November 1, 2026

7-(2-fluoro-4-nitrophenoxy)-1H-pyrrolo[2,3-c]pyridine → 6-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine

https://huagongshe.com/reaction/1261341

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-(2-fluoro-4-nitrophenoxy)-1H-pyrrolo[2,3-c]pyridineHCID 59424641—
Reactant6-Bromo-7-chlorothieno(3,2-b)pyridineHCID 59424655—
Product6-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridineHCID 5942445761%

Reaction Steps

Starting from the compound 271 and following the procedure described above for the synthesis of compound 260 (scheme 59, example 218, step 2), title compound 272 was obtained in 61% yield as an off-white solid. MS (m/z): 368.9(M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470850B2
Source datasetuspto-grants-2013_06
ORD IDord-063d8f552dfb45f293f518ec2eace7b5
Source noteuspto-grants-2013_06