6-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine → 4-(6-Bromothieno[3,2-b]pyridin-7-yloxy)-3-fluorobenzenamine

Participants

Role	Name	HCID	Charge
Reactant	6-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine	HCID 59424457	—
Reactant	4-(1H-Pyrrolo[2,3-c]pyridin-7-yloxy)-3-fluorobenzenamine	HCID 59424629	—
Product	4-(6-Bromothieno[3,2-b]pyridin-7-yloxy)-3-fluorobenzenamine	HCID 59424676	92%

Reaction Steps

Starting from the compound 272 and following the procedure described above for the synthesis of compound 261 (scheme 59, example 218, step 3), title compound 273 was obtained in 92% yield as a light brown solid. MS (m/z): 340.0(M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08470850B2
Source dataset	uspto-grants-2013_06
ORD ID	ord-2d97703c2e0a497c9573be5b3511c661
Source note	uspto-grants-2013_06