HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-N,N-dimethylacetamide → HCID 66591549, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-N,N-dimethylacetamide | HCID 75886 | — |
| Reactant | 1-(Chloroacetyl)pyrrolidine | HCID 88440 | — |
| Reactant | HCID 25018730 | HCID 25018730 | — |
| Product | HCID 66591549 | HCID 66591549 | 74% |
Reaction Steps
This compound was obtained as a brown solid in 74% yield following the same procedure described in Scheme 21 for the synthesis of 2-[[2-[4-fluoro-3-(2,2,2-trifluoro-ethoxy)-phenyl]-ethyl]-(tetrahydrofuran-3-ylmethyl)amino]-N,N-dimethyl-acetamide, using 2-chloro-1-pyrrolidin-1-yl-ethanone as the reagent instead of 2-chloro-N,N-dimethyl-acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08470877B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-f013231e588e4b2a814bd7d4f4ca7d1c |
| Source note | uspto-grants-2013_06 |