HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrabutylammonium Fluoride → Ethyl 4''-diethylamino-4'-(3-hydroxypropoxy)-[1,1';3',1'']terphenyl-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| Reactant | Ethyl 4'-[3-(tert-butyldimethylsilanyloxy)propoxy]-4''-diethylamino[1,1';3',1'']terphenyl-4-carboxylate | HCID 66671878 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Ethyl 4''-diethylamino-4'-(3-hydroxypropoxy)-[1,1';3',1'']terphenyl-4-carboxylate | HCID 11626517 | 74% |
Reaction Steps
In a manner similar to that of Example 2b, by reacting 730 mg of ethyl 4′-[3-(tert-butyldimethylsilanyloxy)propoxy]-4″-diethylamino[1,1′;3′,1″]terphenyl-4-carboxylate (1.3 mmol) in 25 mL of tetrahydrofuran with 1.6 mL of 1M tetrabutylammonium fluoride. 430 mg of ethyl 4″-diethylamino-4′-(3-hydroxypropoxy)-[1,1′;3′,1″]terphenyl-4-carboxylate are obtained (yield=74%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08470871B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-9dbc756a8bb848be85e78b114652b925 |
| Source note | uspto-grants-2013_06 |