HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triisopropyl borate → 4-Diethylamino-3-methylphenylboronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triisopropyl borate | HCID 21531 | — |
| Reactant | 4-Bromo-N,N-diethyl-2-methylbenzenamine | HCID 66672065 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 4-Diethylamino-3-methylphenylboronic acid | HCID 66672056 | 111.2% |
Reaction Steps
In a manner similar to that of Example 1c, by reacting 8 g of (4-bromo-2-methylphenyl)diethylamine (33 mmol) with 16 mL of a 2.5 M solution of n-butyllithium and 11.5 mL (50 mmol) of triisopropyl borate, 7.6 g of 4-diethylamino-3-methylphenylboronic acid (yield=100%) are obtained in the form of a thick oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08470871B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-8377f0c9804a4f1c9dd621a7d17d7825 |
| Source note | uspto-grants-2013_06 |