Ethyl 3'-bromo-4'-[3-(tert-butyldimethylsilanyloxy)propoxy]biphenyl-4-carboxylate → Ethyl 4'-[3-(tert-butyldimethylsilanyloxy)propoxy]-4''-diethylamino-3''-methyl[1,1';3',1'']terphenyl-4-carboxylate

Participants

Reaction Steps

In a manner similar to that of Example 1d, by reacting 1 g (2 mmol) of ethyl 3′-bromo-4′-[3-(tert-butyldimethylsilanyloxy)propoxy]biphenyl-4-carboxylate (obtained in Example 6b) with 630 mg of 4-diethylamino-3-methylphenylboronic acid (3 mmol) in the presence of tetrakis(triphenylphosphine)palladium, 1.1 g of ethyl 4′-[3-(tert-butyldimethylsilanyloxy)propoxy]-4″-diethylamino-3″-methyl[1,1′;3′,1″]terphenyl-4-carboxylate (yield=95%) are obtained in the form of a pale yellow oil.

Provenance & Evidence