2-Cyclohexen-1-one → HCID 58028210, compound

Participants

Reaction Steps

According to Example 2, cyclopentylmagnesium bromide (1.00 M in THF, 2.10 mL; 2.10 mmol; 1.05 equiv) was reacted with cyclohexenone (192 mg; 2.00 mmol) in the presence of LaCl3.2LiCl (0.33 M; 6.06 mL, 2.00 mmol, 1.00 equiv). Gel filtration (silica; pentane:Et2O 9:1, 0.5 vol-% NEt3) afforded 1-Cyclopentyl-cyclohex-2-enol (7) as colorless oil (306 mg, 93%).

Provenance & Evidence