HCID 57913426, compound → HCID 57913428, compound

HRID 1261740Notes

Reaction equation

HRID 1261740 reaction equation
ClC1C=CC([C:8]([C:36]2[CH:41]=[CH:40][C:39]([Cl:42])=[CH:38][CH:37]=2)(OC)[C:9]2[CH:14]=[C:13]([OH:15])[C:12]([C:16](C3C=CC(Cl)=CC=3)([C:19]3[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=3)OC)=[CH:11][C:10]=2[OH:33])=CC=1>[N+](C1C=CC=CC=1)([O-])=O>[Cl:25][C:22]1[CH:23]=[CH:24][C:19]2[C:16]([C:36]3[CH:37]=[CH:38][C:39]([Cl:42])=[CH:40][CH:41]=3)=[C:12]3[C:13](=[CH:14][C:9]4[C:10]([O:33][C:24]5[C:19]([C:8]=4[C:36]4[CH:41]=[CH:40][C:39]([Cl:42])=[CH:38][CH:37]=4)=[CH:20][CH:21]=[C:22]([Cl:25])[CH:23]=5)=[CH:11]3)[O:15][C:20]=2[CH:21]=1

Participants

3

Reactant 1

HCID 57913426HCID 57913426, compound

Product 1

HCID 57913428HCID 57913428, compound

Reagents, catalysts & solvents 1

HCID 7416NitrobenzeneSolvent

Procedure

A solution of the product from example a (2,5-bis-[bis-(4-chloro-phenyl)-methoxy-methyl]-benzene-1,4-diol, 1.0 g, 1.56 mmol) is dissolved in nitrobenzene (5 ml) and the solution heated at reflux. The initially colourless solution turns red and later deeply violet. After one hour at reflux, the mixture is allowed to cool and then filtered. The product (violet needles) is washed with plenty of methanol and dried. MS shows the correct mass and isotopic pattern of four chlorines.

Workup

  1. temperaturethe solution heated
  2. temperatureat reflux
  3. temperatureAfter one hour at reflux
  4. temperatureto cool
  5. filtrationfiltered
  6. washThe product (violet needles) is washed with plenty of methanol
  7. customdried

Sources & evidence

ORD record
ord-4127c95d3fe44494b45401b72239d756
Source dataset
uspto-grants-2013_06
Patent number
US08471019B2

Reaction notes

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