Acetic Acid → HCID 23450598, compound

Participants

Reaction Steps

1.8 g 2,2,6,6-tetramethyl-piperidin-4-ol (intermediate product of Ciba Specialty Chemicals Inc.) are suspended in 7 ml of toluene. 3.6 ml of a 30% aqueous hydrogen peroxide solution and 0.41 g acetic acid are added at 5° C. and the solution is stirred at room temperature over night. 4.2 ml butanal and, after 15 min., 50 mg CuCl are added. The reaction mixture is stirred for 18 h at room temperature. The two phases are separated and the organic one is washed with 0.05M hydrochloric acid, sodium bisulfite solution, water, diluted sodium hydroxide solution, water and finally saturated sodium chloride solution. The organic phase is dried over sodium sulfate and finally evaporated to complete dryness under vacuum to afford 0.38 g product.

Provenance & Evidence