HCID 67319271, compound → HCID 11455037, compound

Participants

Reaction Steps

To a solution of the compound 4u (370 mg, 460 μmol) in dichloromethane (50 mL) was added DCA (1.5 mL). The mixture was stirred for 10 minutes, and washed with 5% aqueous NaHCO3 (3×50 mL). The aqueous layer was back-extracted with dichloromethane (10 mL), and the combined organic layer was dried over Na2SO4, filtered to separate Na2SO4, and dried under reduced pressure. The residue was purified by silica gel chromatography (eluent: 0 to 4% methanol in dichloromethane) to give the objective compound 5u (200 mg, 87%) as white foam.

Provenance & Evidence