huagongshe.com
HRID1262050

反应详情

EQUATION

反应方程式

HRID 1262050 的结构方程式

REACTANTS

反应物

2
结构：COc1cc(N2CCC[C@@H](C(=O)N3CCN(C)CC3)C2)ccc1[N+](=O)[O-]
HCID66711060

未命名化合物

结构：CN1CCN(CC2CCCN(c3ccc([N+](=O)[O-])cc3)C2)CC1
HCID66711445

1-Methyl-4-[[1-(4-nitrophenyl)-3-piperidinyl]methyl]piperazine

C17H26N4O2

PRODUCTS

生成物

1
结构：COc1cc(N2CCC[C@@H](CN3CCN(C)CC3)C2)ccc1[N+](=O)[O-]
HCID66711617

未命名化合物

PROCEDURE

实验过程

1-[(S)-1-(3-Methoxy-4-nitro-phenyl)-piperidin-3-ylmethyl]-4-methyl-piperazine was prepared in an analogous fashion to 1-Methyl-4-[1-(4-nitro-phenyl)-piperidin-3-ylmethyl]-piperazine of Example 455a replacing (4-Methyl-piperazin-1-yl)-[1-(4-nitro-phenyl)-piperidin-3-yl]-methanone with [(R)-1-(3-Methoxy-4-nitro-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone. 1-[(S)-1-(3-Methoxy-4-nitro-phenyl)-piperidin-3-ylmethyl]-4-methyl-piperazine was isolated as an orange oil (170 mg, 43%). LC/MS (E/I+) 349.24 (M+H).