HRID1262055

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1cc(N2CCC(N(C)C)CC2)ccc1[N+](=O)[O-]

HCID57416152

1-(3-Methoxy-4-nitrophenyl)-N,N-dimethylpiperidin-4-amine

C14H21N3O3

结构：COc1cc(N2CCC[C@H](C(=O)N3CCN(C)CC3)C2)ccc1N

HCID66711468

未命名化合物

PRODUCTS

生成物

HCID57416153

1-(4-Amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine

C14H23N3O

PROCEDURE

实验过程

[1-(4-Amino-3-methoxy-phenyl)-piperidin-4-yl]-dimethyl-amine was prepared in an analogous fashion to [(S)-1-(4-Amino-3-methoxy-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone of Example 460c replacing [(S)-1-(3-Methoxy-4-nitro-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone with [1-(3-Methoxy-4-nitro-phenyl)-piperidine-4-yl]dimethyl-amine (280 mg, 100%). LC/MS (E/I+) 249 (M+H).