HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66711468, compound → [4-(4-Amino-phenyl)-piperidin-1-yl]-(1-methyl-piperidin-4-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66711468 | HCID 66711468 | — |
| Reactant | (1-Methyl-piperidin-4-yl)-[4-(4-nitro-phenyl)-piperidin-1-yl]-methanone | HCID 66711904 | — |
| Product | [4-(4-Amino-phenyl)-piperidin-1-yl]-(1-methyl-piperidin-4-yl)-methanone | HCID 66711641 | — |
Reaction Steps
[4-(4-Amino-phenyl)-piperidin-1-yl]-(1-methyl-piperidin-4-yl)-methanone was prepared in an analogous fashion to [(S)-1-(4-Amino-3-methoxy-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone of Example 460c replacing [(S)-1-(3-Methoxy-4-nitro-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone with (1-Methyl-piperidin-4-yl)-[4-(4-nitro-phenyl)-piperidin-1-yl]-methanone. LC/MS (E/I+) 302.15 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08471005B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-03be891f0ac641b0a93cc1326fbf5849 |
| Source note | uspto-grants-2013_06 |