7-Methyl-6-nitro-1,3-benzoxazol-2(3H)-one → 6-Amino-7-methyl-1,3-benzoxazol-2(3H)-one

Participants

Reaction Steps

7-Methyl-6-nitro-3H-benzoxazol-2-one (0.895 g, 4.61 mmol) was hydrogenated in Methanol (30.0 mL) over 10% Palladium on Carbon (50% Wet) (0.135 g, 0.0634 mmol) under an atmosphere of Hydrogen (30 psi) for 2 h. The mixture was filtered through Celite, washed with MeOH and conc. in vacuo to afford 6-Amino-7-methyl-3H-benzoxazol-2-one (0.74 g, 98%).

Provenance & Evidence