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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1262455Generated: November 2, 2026

HCID 4350219, compound → HCID 13290537, compound

https://huagongshe.com/reaction/1262455

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 4350219HCID 4350219—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 13290537HCID 13290537—

Reaction Steps

1B, in tetrahydrofuran, was treated with hydrogen (40 psi pressure in a Parr-shaker, 10% palladium-on-carbon catalyst), to give ethyl 2-(4-(2-amino-4-(trifluoromethyl)phenylamino)phenoxy)propionate (1C), as a solid, m.p.: 78° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04452626
Source datasetuspto-grants-1984_06
ORD IDord-525ce7430103472ab13ec18d2d718362
Source noteuspto-grants-1984_06