Pyrrolidone carboxylic acid → HCID 23320543, compound

HRID 1262646Notes

Reaction equation

HRID 1262646 reaction equation
[NH:1]1[CH:5]([C:6]([OH:8])=O)[CH2:4][CH2:3][C:2]1=[O:9].[CH3:10][N:11]([CH2:13][CH2:14][CH2:15][NH2:16])[CH3:12]>>[CH3:10][N:11]([CH3:12])[CH2:13][CH2:14][CH2:15][NH:16][C:6]([CH:5]1[CH2:4][CH2:3][C:2](=[O:9])[NH:1]1)=[O:8]

Participants

3

Reactant 2

HCID 499Pyrrolidone carboxylic acidHCID 7993N,N-Dimethyl-1,3-propanediamine

Product 1

HCID 23320543HCID 23320543, compound

Conditions

Temperature
165 °C

Procedure

129 Grams of 2-pyrrolidone-5-carboxylic acid were slowly added to 133 g of dimethylaminopropylamine with mixing. This mixture was then stirred and heated for 8-10 hours at 165° C. The excess amine was then distilled off having the title product in the form of an amber colored water-soluble solid.

Workup

  1. additionwith mixing
  2. distillationThe excess amine was then distilled off

Sources & evidence

ORD record
ord-6c91151282b140299ac101cfa87adf6c
Source dataset
uspto-grants-1984_06
Patent number
US04452989

Reaction notes

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