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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 126274Generated: October 25, 2026

Water → 6-chloro-2-pyrazin-2-yl-5-(2,4,6-trifluorophenyl)-N-(1,1,1-trifluoropropan-2-yl)pyrimidin-4-amine

https://huagongshe.com/reaction/126274

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantIsopropanolHCID 3776—
ReactantN-methyl-2-pyrrolidoneHCID 13387—
Reactant1,1,1-Trifluoro-2-propanamineHCID 3783165—
Reactant4,6-Dichloro-2-(pyrazin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidineHCID 58910101—
Product6-chloro-2-pyrazin-2-yl-5-(2,4,6-trifluorophenyl)-N-(1,1,1-trifluoropropan-2-yl)pyrimidin-4-amineHCID 11293429—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-04021cd3686042f48d254f71c22aa23c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)