Tert-Butylamine → HCID 13138209, 화합물

HRID 1262797노트

반응식

HRID 1262797 반응식
[N:1]([C:4]1[CH:5]=[C:6]([S:10]([NH:13][C:14]([NH:16][C:17]2[N:22]=[C:21]([O:23][CH3:24])[CH:20]=[C:19]([CH3:25])[N:18]=2)=[O:15])(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1)=[C:2]=[O:3].[C:26]([NH2:30])([CH3:29])([CH3:28])[CH3:27]>>[C:26]([NH:30][C:2](=[O:3])[NH:1][C:4]1[CH:5]=[C:6]([S:10]([NH:13][C:14]([NH:16][C:17]2[N:22]=[C:21]([O:23][CH3:24])[CH:20]=[C:19]([CH3:25])[N:18]=2)=[O:15])(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1)([CH3:29])([CH3:28])[CH3:27]

참가 물질

3

반응물 2

HCID 6385Tert-ButylamineHCID 204558693-isocyanato-N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]benzenesulfonamide

생성물 1

HCID 13138209HCID 13138209, 화합물

실험 절차

To a solution of 3-isocyanato-N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]benzenesulfonamide prepared as in Example 3 was added 0.8 g of tert-butylamine at ambient temperature with stirring. After sixteen hours, filtration of the reaction mixture and evaporation of the filtrate yielded the desired product which after trituration with ethyl ether and isolation by filtration melted at 137°-145°.

후처리

  1. waitAfter sixteen hours
  2. filtrationfiltration of the reaction mixture and evaporation of the filtrate

출처 및 근거

ORD 기록
ord-1ca19dc476d04383b36462fdf50d5be3
출처 데이터셋
uspto-grants-1984_06
특허 번호
US04453971

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