HuagongsheHuagongshe Chemistry Print Report · For research reference only
Alloxan → 5-(4-bromo-2-furyl)-2,4,6(1H,3H,5H)pyrimidinetrione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Alloxan | HCID 5781 | — |
| Reactant | 2,4-Dibromofuran | HCID 12572398 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 5-(4-bromo-2-furyl)-2,4,6(1H,3H,5H)pyrimidinetrione | HCID 20456479 | — |
Reaction Steps
n-Butyl lithium is reacted with 2,4-dibromofuran in ether according to the procedure of Sornay et al. [Bull. soc. chim. Fr., p. 998 (1971)]. The resulting organolithium solution is reacted with alloxan at -60° to -65° C. according to Example 5, affording 5-(4-bromo-2-furyl)-2,4,6(1H,3H,5H)pyrimidinetrione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04454320 |
| Source dataset | uspto-grants-1984_06 |
| ORD ID | ord-c20c0adc9c3c4317a5708bb572269377 |
| Source note | uspto-grants-1984_06 |