HuagongsheHuagongshe Chemistry Print Report · For research reference only
Alloxan → HCID 86739478, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Alloxan | HCID 5781 | — |
| Reactant | 2-Bromoanisole | HCID 11358 | — |
| Reactant | 2-Chloroanisole | HCID 13011 | — |
| Reactant | o-Iodoanisole | HCID 68257 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Solvent | Diisopropyl Ether | HCID 7914 | — |
| Product | HCID 86739478 | HCID 86739478 | — |
Reaction Steps
Alternatively, 2-chloroanisole, 2-bromoanisole or 2-iodoanisole is converted to the corresponding Grignard reagent by reaction with magnesium turnings in diisopropyl ether. The reagent is chilled and reacted with anhydrous alloxan according to Example 5 to yield 5-(hydroxy-5-(2-methoxyphenyl)-2,4,6(1H,3H,5H)pyrimidintrione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04454320 |
| Source dataset | uspto-grants-1984_06 |
| ORD ID | ord-540dd4e27ec845d5a10c871f5df224ea |
| Source note | uspto-grants-1984_06 |