HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 13178725, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2-Nitrobenzyl chloride | HCID 11921 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Solvent | Butyl Chloride | HCID 8005 | — |
| Product | HCID 13178725 | HCID 13178725 | 83.7% |
Reaction Steps
A solution of 153.9 g of o-nitrobenzylchloride and 68.5 g of thiourea in 900 ml of #2B ethanol was stirred at reflux temperature (80°) for 11/4 hours. The solution was cooled to 60° and 1.1 liters of 1-chlorobutane was added. Further cooling to 15° produced a heavy precipitate. The precipitate was filtered, washed with 1-chlorobutane and dried to yield 185.9 g of 2-nitrophenylmethyl carbamimidothioate hydrochloride, m.p. 190°-192°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04454334 |
| Source dataset | uspto-grants-1984_06 |
| ORD ID | ord-5e9c3fbca6eb4cd2b4169621f1a67606 |
| Source note | uspto-grants-1984_06 |