反应详情

To mixture composed of 68 g (0.48 mol) of N-methacryloyl glycine obtained in the above described manner and 46 g (0.2 mol) of 6-amino-2,4-dichloro-3-methylphenol hydrochloride were added 114 ml (1.44 mol) of pyridine and 1 liter of ethyl acetate and stirred under cooling. To the solution was added dropwise 29 ml (0.4 mol) of thionyl chloride. After the completion of the reaction, 300 ml of water was added to the reaction solution and extracted with ethyl acetate. The ethyl acetate solution was concentrated and to the residue was added acetonitrile. The crystals thus deposited were collected and recrystallized from acetonitrile to obtain 34.8 g of Monomer Coupler (2).

1. customobtained in the
2. temperatureunder cooling
3. additionwas added to the reaction solution
4. extractionextracted with ethyl acetate
5. concentrationThe ethyl acetate solution was concentrated and to the residue
6. additionwas added acetonitrile
7. customThe crystals thus deposited were collected
8. customrecrystallized from acetonitrile