Potassium Hydroxide → HCID 20256655, compound

HRID 1263195Notes

Reaction equation

HRID 1263195 reaction equation
[CH3:1][P:2]([CH:7]([O:9][C:10]1[CH:15]=[C:14]([O:16][C:17]2[CH:22]=[CH:21][C:20]([C:23]([F:26])([F:25])[F:24])=[CH:19][C:18]=2[Cl:27])[CH:13]=[CH:12][C:11]=1[N+:28]([O-:30])=[O:29])[CH3:8])(=[O:6])[O:3]CC.[OH-].[K+]>C(O)C.O>[CH3:1][P:2]([CH:7]([O:9][C:10]1[CH:15]=[C:14]([O:16][C:17]2[CH:22]=[CH:21][C:20]([C:23]([F:25])([F:24])[F:26])=[CH:19][C:18]=2[Cl:27])[CH:13]=[CH:12][C:11]=1[N+:28]([O-:30])=[O:29])[CH3:8])(=[O:3])[OH:6]

Participants

5

Reactant 2

HCID 14797Potassium HydroxideHCID 13536726HCID 13536726, compound

Product 1

HCID 20256655HCID 20256655, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

To ethyl P-methyl-α-[2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenoxy]ethylphosphinate (1.1 g) in ethanol (10 ml) is added potassium hydroxide (0.5 g) in water (15 ml). The mixture is stirred at RT for 4 hours. The ethanol is removed, and the aqueous solution is acidified and extracted with ether. The combined extracts are dried and evaporated to dryness to give P-methyl-α-[2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenoxy]-ethylphosphinic acid.

Workup

  1. customThe ethanol is removed
  2. extractionextracted with ether
  3. customThe combined extracts are dried
  4. customevaporated to dryness

Sources & evidence

ORD record
ord-148ebc0e77bb487aafcfbaec8c545f9c
Source dataset
uspto-grants-1984_06
Patent number
US04456464

Reaction notes

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