Acetic Anhydride → 4,5-Dichlorophthalic anhydride

HRID 1263216Notes

Reaction equation

HRID 1263216 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:12]([OH:14])=[O:13])[C:5](=[CH:9][C:10]=1[Cl:11])[C:6]([OH:8])=O.C(OC(=O)C)(=O)C>>[Cl:11][C:10]1[CH:9]=[C:5]2[C:6](=[O:8])[O:14][C:12](=[O:13])[C:4]2=[CH:3][C:2]=1[Cl:1]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 926004,5-Dichlorophthalic acid

Product 1

HCID 703344,5-Dichlorophthalic anhydride

Procedure

4,5-Dichlorophthalic acid (30 g., 0.127 mole) is refluxed in 150 ml. of acetic anhydride for 3 hours. The acetic anhydride is evaporated and the residue is triturated with diethyl ether and filtered to give a quantitative yield of 4,5-dichlorophthalic anhydride. The crude product is recrystallized from ethyl acetate and hexane.

Workup

  1. customThe acetic anhydride is evaporated
  2. customthe residue is triturated with diethyl ether
  3. filtrationfiltered

Sources & evidence

ORD record
ord-c7c9143125c344a7ad29409698d7dbb8
Source dataset
uspto-grants-1984_06
Patent number
US04456595

Reaction notes

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