3-Nitrophthalic acid → 3-Aminophthalic acid

Participants

Reaction Steps

A commercial sample of 3-nitrophthalic acid (20% 4-nitro by TLC) is dissolved in 150 ml. of hot water, filtered and cooled for 2 hours to give 13 g. of pure 3-nitrophthalic acid as a white solid. The recrystallized 3-nitrophthalic acid (13 g., 0.062 mole) is dissolved in methanol (200 ml.) and hydrogenated over platinic oxide (50 mg.) at 25 psi. When uptake ceases (one hour), the mixture is filtered and evaporated to 12.4 g. of solid 3-aminophthalic acid.

Provenance & Evidence