1,3-Benzodioxole-5-carboxylic acid, hydrazide → HCID 70510198, compound

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Reaction Steps

2.0 g. (0.005 moles) of 9,9-dibromo-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid ethyl ester and 0.9 g. (0.005 moles) of piperonylic acid hydrazide are dissolved in 80 ml. of pyridine. The solution is allowed to stand for two days whereupon the solvent is distilled off in vacuo. To the residue 30 ml. of water are added. After a short standing the crystals are filtered off and recrystallized from methanol. 0.5 g. (24.2%) of 6-methyl-9-(3,4-methylenedioxybenzoylhydrazono)-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid ethyl ester are obtained, melting at 183° to 185° C.

Provenance & Evidence